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Effects of Early IL-17A Neutralization on Disease Induction in a Primate Model of Experimental Autoimmune Encephalomyelitis

We report on the effect of antibody-mediated neutralization of interleukin (IL)-17A in a non-human primate experimental autoimmune encephalomyelitis (EAE) model induced with recombinant human myelin oligodendrocyte glycoprotein (rhMOG). We tested a human-anti-human IL-17A-antibody in two doses (3 an...

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Detalles Bibliográficos
Autores principales: Kap, Yolanda S., Jagessar, S. Anwar, van Driel, Nikki, Blezer, Erwin, Bauer, Jan, van Meurs, Marjan, Smith, Paul, Laman, Jon D., ‘t Hart, Bert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128270/
https://www.ncbi.nlm.nih.gov/pubmed/20700661
http://dx.doi.org/10.1007/s11481-010-9238-3