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Effects of Early IL-17A Neutralization on Disease Induction in a Primate Model of Experimental Autoimmune Encephalomyelitis
We report on the effect of antibody-mediated neutralization of interleukin (IL)-17A in a non-human primate experimental autoimmune encephalomyelitis (EAE) model induced with recombinant human myelin oligodendrocyte glycoprotein (rhMOG). We tested a human-anti-human IL-17A-antibody in two doses (3 an...
Autores principales: | Kap, Yolanda S., Jagessar, S. Anwar, van Driel, Nikki, Blezer, Erwin, Bauer, Jan, van Meurs, Marjan, Smith, Paul, Laman, Jon D., ‘t Hart, Bert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128270/ https://www.ncbi.nlm.nih.gov/pubmed/20700661 http://dx.doi.org/10.1007/s11481-010-9238-3 |
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