Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis

OBJECTIVES: Methotrexate (MTX) is the mainstay treatment for juvenile idiopathic arthritis (JIA), however approximately 30% of children will fail to respond to the drug. Identification of genetic predictors of response to MTX would be invaluable in developing optimal treatment strategies for JIA. Us...

Descripción completa

Detalles Bibliográficos
Autores principales: Hinks, Anne, Moncrieffe, Halima, Martin, Paul, Ursu, Simona, Lal, Sham, Kassoumeri, Laura, Weiler, Tracey, Glass, David N, Thompson, Susan D, Wedderburn, Lucy R, Thomson, Wendy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2011
Materias:
Clinical and Epidemiological Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128324/
https://www.ncbi.nlm.nih.gov/pubmed/21515602
http://dx.doi.org/10.1136/ard.2010.146191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128324/
https://www.ncbi.nlm.nih.gov/pubmed/21515602
http://dx.doi.org/10.1136/ard.2010.146191

Ejemplares similares