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Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis

OBJECTIVES: Methotrexate (MTX) is the mainstay treatment for juvenile idiopathic arthritis (JIA), however approximately 30% of children will fail to respond to the drug. Identification of genetic predictors of response to MTX would be invaluable in developing optimal treatment strategies for JIA. Us...

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Detalles Bibliográficos
Autores principales:	Hinks, Anne, Moncrieffe, Halima, Martin, Paul, Ursu, Simona, Lal, Sham, Kassoumeri, Laura, Weiler, Tracey, Glass, David N, Thompson, Susan D, Wedderburn, Lucy R, Thomson, Wendy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Group 2011
Materias:	Clinical and Epidemiological Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128324/ https://www.ncbi.nlm.nih.gov/pubmed/21515602 http://dx.doi.org/10.1136/ard.2010.146191

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