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Administration of PPARβ/δ agonist reduces copper-induced liver damage in mice: possible implications in clinical practice
In this study we investigated if peroxisome proliferator-activated receptor β/δ activation protects from copper-induced acute liver damage. Mice treated with copper had significant body weight loss, serum alanine aminotransferase increase, modest changes in liver histology, increase of tumor necrosi...
Autores principales: | Sanchez-Siles, Alvaro A., Ishimura, Norihisa, Rumi, Mohammad A. K., Tamagawa, Yuji, Ito, Satoko, Ishihara, Shunji, Nabika, Toru, Kinoshita, Yoshikazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
the Society for Free Radical Research Japan
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128365/ https://www.ncbi.nlm.nih.gov/pubmed/21765606 http://dx.doi.org/10.3164/jcbn.10-139 |
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