The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells

Previous studies using in vitro cell culture systems have shown the role of the dynamin-related GTPase Opa1 in apoptosis prevention and mitochondrial DNA (mtDNA) maintenance. However, it remains to be tested whether these functions of Opa1 are physiologically important in vivo in mammals. Here, usin...

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Detalles Bibliográficos
Autores principales: Zhang, Zhongyan, Wakabayashi, Nobunao, Wakabayashi, Junko, Tamura, Yasushi, Song, Woo-Jin, Sereda, Sam, Clerc, Pascaline, Polster, Brian M., Aja, Susan M., Pletnikov, Mikhail V., Kensler, Thomas W., Shirihai, Orian S., Iijima, Miho, Hussain, Mehboob A., Sesaki, Hiromi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128526/
https://www.ncbi.nlm.nih.gov/pubmed/21551073
http://dx.doi.org/10.1091/mbc.E10-12-0933

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