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Dictyostelium huntingtin controls chemotaxis and cytokinesis through the regulation of myosin II phosphorylation

Abnormalities in the huntingtin protein (Htt) are associated with Huntington's disease. Despite its importance, the function of Htt is largely unknown. We show that Htt is required for normal chemotaxis and cytokinesis in Dictyostelium discoideum. Cells lacking Htt showed slower migration towar...

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Detalles Bibliográficos
Autores principales:	Wang, Yu, Steimle, Paul A., Ren, Yixin, Ross, Christopher A., Robinson, Douglas N., Egelhoff, Thomas T., Sesaki, Hiromi, Iijima, Miho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128529/ https://www.ncbi.nlm.nih.gov/pubmed/21562226 http://dx.doi.org/10.1091/mbc.E10-11-0926

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