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Construction of uricase-overproducing strains of Hansenula polymorpha and its application as biological recognition element in microbial urate biosensor

BACKGROUND: The detection and quantification of uric acid in human physiological fluids is of great importance in the diagnosis and therapy of patients suffering from a range of disorders associated with altered purine metabolism, most notably gout and hyperuricaemia. The fabrication of cheap and re...

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Detalles Bibliográficos
Autores principales:	Dmytruk, Kostyantyn V, Smutok, Oleh V, Dmytruk, Olena V, Schuhmann, Wolfgang, Sibirny, Andriy A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128571/ https://www.ncbi.nlm.nih.gov/pubmed/21612631 http://dx.doi.org/10.1186/1472-6750-11-58

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