A Novel Nonsense Mutation in the DMP1 Gene Identified by a Genome-Wide Association Study Is Responsible for Inherited Rickets in Corriedale Sheep

Inherited rickets of Corriedale sheep is characterized by decreased growth rate, thoracic lordosis and angular limb deformities. Previous outcross and backcross studies implicate inheritance as a simple autosomal recessive disorder. A genome wide association study was conducted using the Illumina Ov...

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Detalles Bibliográficos
Autores principales: Zhao, Xia, Dittmer, Keren E., Blair, Hugh T., Thompson, Keith G., Rothschild, Max F., Garrick, Dorian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128599/
https://www.ncbi.nlm.nih.gov/pubmed/21747952
http://dx.doi.org/10.1371/journal.pone.0021739

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