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Fatal Outcome in Bacteremia is Characterized by High Plasma Cell Free DNA Concentration and Apoptotic DNA Fragmentation: A Prospective Cohort Study

INTRODUCTION: Recent studies have shown that apoptosis plays a critical role in the pathogenesis of sepsis. High plasma cell free DNA (cf-DNA) concentrations have been shown to be associated with sepsis outcome. The origin of cf-DNA is unclear. METHODS: Total plasma cf-DNA was quantified directly in...

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Detalles Bibliográficos
Autores principales:	Huttunen, Reetta, Kuparinen, Taru, Jylhävä, Juulia, Aittoniemi, Janne, Vuento, Risto, Huhtala, Heini, Laine, Janne, Syrjänen, Jaana, Hurme, Mikko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128600/ https://www.ncbi.nlm.nih.gov/pubmed/21747948 http://dx.doi.org/10.1371/journal.pone.0021700

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