Potential involvement of F(0)F(1)-ATP(synth)ase and reactive oxygen species in apoptosis induction by the antineoplastic agent erucylphosphohomocholine in glioblastoma cell lines: A mechanism for induction of apoptosis via the 18 kDa mitochondrial translocator protein

Erucylphosphohomocholine (ErPC3, Erufosine™) was reported previously to induce apoptosis in otherwise highly apoptosis-resistant malignant glioma cell lines while sparing their non-tumorigenic counterparts. We also previously found that the mitochondrial 18 kDa Translocator Protein (TSPO) is require...

Descripción completa

Detalles Bibliográficos
Autores principales: Veenman, Leo, Alten, Julia, Linnemannstöns, Karen, Shandalov, Yulia, Zeno, Sivan, Lakomek, Max, Gavish, Moshe, Kugler, Wilfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128697/
https://www.ncbi.nlm.nih.gov/pubmed/20107899
http://dx.doi.org/10.1007/s10495-010-0460-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128697/
https://www.ncbi.nlm.nih.gov/pubmed/20107899
http://dx.doi.org/10.1007/s10495-010-0460-5

Ejemplares similares