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Potential involvement of F(0)F(1)-ATP(synth)ase and reactive oxygen species in apoptosis induction by the antineoplastic agent erucylphosphohomocholine in glioblastoma cell lines: A mechanism for induction of apoptosis via the 18 kDa mitochondrial translocator protein
Erucylphosphohomocholine (ErPC3, Erufosine™) was reported previously to induce apoptosis in otherwise highly apoptosis-resistant malignant glioma cell lines while sparing their non-tumorigenic counterparts. We also previously found that the mitochondrial 18 kDa Translocator Protein (TSPO) is require...
Autores principales: | Veenman, Leo, Alten, Julia, Linnemannstöns, Karen, Shandalov, Yulia, Zeno, Sivan, Lakomek, Max, Gavish, Moshe, Kugler, Wilfried |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128697/ https://www.ncbi.nlm.nih.gov/pubmed/20107899 http://dx.doi.org/10.1007/s10495-010-0460-5 |
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