Microscale to Manufacturing Scale-up of Cell-Free Cytokine Production—A New Approach for Shortening Protein Production Development Timelines

Engineering robust protein production and purification of correctly folded biotherapeutic proteins in cell-based systems is often challenging due to the requirements for maintaining complex cellular networks for cell viability and the need to develop associated downstream processes that reproducibly...

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Detalles Bibliográficos
Autores principales: Zawada, James F, Yin, Gang, Steiner, Alexander R, Yang, Junhao, Naresh, Alpana, Roy, Sushmita M, Gold, Daniel S, Heinsohn, Henry G, Murray, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128707/
https://www.ncbi.nlm.nih.gov/pubmed/21337337
http://dx.doi.org/10.1002/bit.23103

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