Severe acquired cytomegalovirus infection in a full-term, formula-fed infant: Case Report

BACKGROUND: Cases of cytomegalovirus colitis are exceptionally reported in immuno-competent infant. The pathogenesis is uncertain but breast-feeding is considered as a main source of postnatal infection. CASE PRESENTATION: Here we report a full-term, formula-fed infant who developed a severe cytomeg...

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Autores principales: Berardi, Alberto, Rossi, Cecilia, Fiorini, Valentina, Rivi, Cristina, Vagnarelli, Federica, Guaraldi, Nicola, Pietrosemoli, Paola, Lazzarotto, Tiziana, Ferrari, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129307/
https://www.ncbi.nlm.nih.gov/pubmed/21645352
http://dx.doi.org/10.1186/1471-2431-11-52
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author Berardi, Alberto
Rossi, Cecilia
Fiorini, Valentina
Rivi, Cristina
Vagnarelli, Federica
Guaraldi, Nicola
Pietrosemoli, Paola
Lazzarotto, Tiziana
Ferrari, Fabrizio
author_facet Berardi, Alberto
Rossi, Cecilia
Fiorini, Valentina
Rivi, Cristina
Vagnarelli, Federica
Guaraldi, Nicola
Pietrosemoli, Paola
Lazzarotto, Tiziana
Ferrari, Fabrizio
author_sort Berardi, Alberto
collection PubMed
description BACKGROUND: Cases of cytomegalovirus colitis are exceptionally reported in immuno-competent infant. The pathogenesis is uncertain but breast-feeding is considered as a main source of postnatal infection. CASE PRESENTATION: Here we report a full-term, formula-fed infant who developed a severe cytomegalovirus anaemia and colitis when aged 2 months. CONCLUSION: Even if the molecular identity between the cytomegalovirus-isolate of the infant and the maternal virus could not be demonstrated, we confirmed through laboratory investigation that cytomegalovirus infection was acquired postnatally. However, the source of cytomegalovirus infection remained unclear. Alternative modes of cytomegalovirus transmission are discussed.
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spelling pubmed-31293072011-07-05 Severe acquired cytomegalovirus infection in a full-term, formula-fed infant: Case Report Berardi, Alberto Rossi, Cecilia Fiorini, Valentina Rivi, Cristina Vagnarelli, Federica Guaraldi, Nicola Pietrosemoli, Paola Lazzarotto, Tiziana Ferrari, Fabrizio BMC Pediatr Case Report BACKGROUND: Cases of cytomegalovirus colitis are exceptionally reported in immuno-competent infant. The pathogenesis is uncertain but breast-feeding is considered as a main source of postnatal infection. CASE PRESENTATION: Here we report a full-term, formula-fed infant who developed a severe cytomegalovirus anaemia and colitis when aged 2 months. CONCLUSION: Even if the molecular identity between the cytomegalovirus-isolate of the infant and the maternal virus could not be demonstrated, we confirmed through laboratory investigation that cytomegalovirus infection was acquired postnatally. However, the source of cytomegalovirus infection remained unclear. Alternative modes of cytomegalovirus transmission are discussed. BioMed Central 2011-06-06 /pmc/articles/PMC3129307/ /pubmed/21645352 http://dx.doi.org/10.1186/1471-2431-11-52 Text en Copyright ©2011 Berardi et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Berardi, Alberto
Rossi, Cecilia
Fiorini, Valentina
Rivi, Cristina
Vagnarelli, Federica
Guaraldi, Nicola
Pietrosemoli, Paola
Lazzarotto, Tiziana
Ferrari, Fabrizio
Severe acquired cytomegalovirus infection in a full-term, formula-fed infant: Case Report
title Severe acquired cytomegalovirus infection in a full-term, formula-fed infant: Case Report
title_full Severe acquired cytomegalovirus infection in a full-term, formula-fed infant: Case Report
title_fullStr Severe acquired cytomegalovirus infection in a full-term, formula-fed infant: Case Report
title_full_unstemmed Severe acquired cytomegalovirus infection in a full-term, formula-fed infant: Case Report
title_short Severe acquired cytomegalovirus infection in a full-term, formula-fed infant: Case Report
title_sort severe acquired cytomegalovirus infection in a full-term, formula-fed infant: case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129307/
https://www.ncbi.nlm.nih.gov/pubmed/21645352
http://dx.doi.org/10.1186/1471-2431-11-52
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