Cargando…

Intraflagellar transport delivers tubulin isotypes to sensory cilium middle and distal segments

Sensory cilia are assembled and maintained by kinesin-2-dependent intraflagellar transport (IFT). We investigated if two C. elegans α- and β-tubulin isotypes, identified via mutants that lack their cilium distal segments, are delivered to their assembly sites by IFT. Mutations in conserved residues...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hao, Limin, Thein, Melanie, Brust-Mascher, Ingrid, Civelekoglu-Scholey, Gul, Lu, Yun, Acar, Seyda, Prevo, Bram, Shaham, Shai, Scholey, Jonathan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129367/ https://www.ncbi.nlm.nih.gov/pubmed/21642982 http://dx.doi.org/10.1038/ncb2268

Ejemplares similares

Mechanism for Anaphase B: Evaluation of “Slide-and-Cluster” versus “Slide-and-Flux-or-Elongate” Models
por: Brust-Mascher, Ingrid, et al.
Publicado: (2015)

Anaphase B
por: Scholey, Jonathan M., et al.
Publicado: (2016)

Patronin mediates a switch from kinesin-13–dependent poleward flux to anaphase B spindle elongation
por: Wang, Haifeng, et al.
Publicado: (2013)

Dynamic partitioning of mitotic kinesin-5 cross-linkers between microtubule-bound and freely diffusing states
por: Cheerambathur, Dhanya K., et al.
Publicado: (2008)

Prometaphase spindle maintenance by an antagonistic motor-dependent force balance made robust by a disassembling lamin-B envelope
por: Civelekoglu-Scholey, Gul, et al.
Publicado: (2010)

Quantitative analysis of an anaphase B switch: predicted role for a microtubule catastrophe gradient
por: Cheerambathur, Dhanya K., et al.
Publicado: (2007)

Mitotic force generators and chromosome segregation
por: Civelekoglu-Scholey, Gul, et al.
Publicado: (2010)

Intraflagellar transport motors in cilia: moving along the cell's antenna
por: Scholey, Jonathan M.
Publicado: (2008)

Reverse engineering of force integration during mitosis in the Drosophila embryo
por: Wollman, Roy, et al.
Publicado: (2008)

Why motor proteins team up - Intraflagellar transport in C. elegans cilia
por: Mijalkovic, Jona, et al.
Publicado: (2016)

The microtubule cross-linker Feo controls the midzone stability, motor composition, and elongation of the anaphase B spindle in Drosophila embryos
por: Wang, Haifeng, et al.
Publicado: (2015)

Regulation of cilium length and intraflagellar transport by the MAP kinases MAK, MRK, and MOK
por: Jansen, G, et al.
Publicado: (2012)

Anaphase B spindle dynamics in Drosophila S2 cells: Comparison with embryo spindles
por: de Lartigue, Jane, et al.
Publicado: (2011)

Cilium-autonomous regulation of tubulin transport by IFT
por: Lechtreck, K
Publicado: (2015)

Regulation of Cilium Length and Intraflagellar Transport by the RCK-Kinases ICK and MOK in Renal Epithelial Cells
por: Broekhuis, Joost R., et al.
Publicado: (2014)

Tubulin isotype regulation maintains asymmetric requirement for α-tubulin over β-tubulin
por: Wethekam, Linnea C., et al.
Publicado: (2023)

The Expression and Function of Tubulin Isotypes in Caenorhabditis elegans
por: Lu, Yu-Ming, et al.
Publicado: (2022)

Taxol acts differently on different tubulin isotypes
por: Chew, Yean Ming, et al.
Publicado: (2023)

Differential utilization of beta-tubulin isotypes in differentiating neurites
Publicado: (1989)

Regulation of microtubule motors by tubulin isotypes and posttranslational modifications
por: Sirajuddin, Minhajuddin, et al.
Publicado: (2014)

Dynamic bonds and polar ejection force distribution explain kinetochore oscillations in PtK1 cells
por: Civelekoglu-Scholey, Gul, et al.
Publicado: (2013)

Dynamic bonds and polar ejection force distribution explain kinetochore oscillations in PtK1 cells
por: Civelekoglu-Scholey, Gul, et al.
Publicado: (2013)

The mammalian beta-tubulin repertoire: hematopoietic expression of a novel, heterologous beta-tubulin isotype
Publicado: (1986)

CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium
por: Lee, Ji Eun, et al.
Publicado: (2012)

Five mouse tubulin isotypes and their regulated expression during development
Publicado: (1985)

Isotypes of alpha-tubulin are differentially regulated during neuronal maturation
Publicado: (1987)

Fasciola hepatica expresses multiple α- and β-tubulin isotypes
por: Ryan, Louise A., et al.
Publicado: (2008)

Tubulin Isotypes and Posttranslational Modifications in Vascular Dementia and Alzheimer’s Disease
por: Santiago-Mujika, Estibaliz, et al.
Publicado: (2022)

In vivo microtubules are copolymers of available beta-tubulin isotypes: localization of each of six vertebrate beta-tubulin isotypes using polyclonal antibodies elicited by synthetic peptide antigens
Publicado: (1987)

Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors
por: Pan, Xiaoyu, et al.
Publicado: (2006)

Copolymerization of two distinct tubulin isotypes during microtubule assembly in vitro
Publicado: (1990)

The Roles of β-Tubulin Mutations and Isotype Expression in Acquired Drug Resistance
por: Huzil, J. Torin, et al.
Publicado: (2007)

Distinct effects of tubulin isotype mutations on neurite growth in Caenorhabditis elegans
por: Zheng, Chaogu, et al.
Publicado: (2017)

An Emerging Role for Tubulin Isotypes in Modulating Cancer Biology and Chemotherapy Resistance
por: Parker, Amelia L., et al.
Publicado: (2017)

Tubulin Isotypes: Emerging Roles in Defining Cancer Stem Cell Niche
por: Maliekal, Tessy Thomas, et al.
Publicado: (2022)

Regulation of Tubulin Gene Expression: From Isotype Identity to Functional Specialization
por: Gasic, Ivana
Publicado: (2022)

Microtubules in Microorganisms: How Tubulin Isotypes Contribute to Diverse Cytoskeletal Functions
por: Bera, Abesh, et al.
Publicado: (2022)

Tubulin transport by IFT is upregulated during ciliary growth by a cilium-autonomous mechanism
por: Craft, Julie M., et al.
Publicado: (2015)

The structured core of human β tubulin confers isotype-specific polymerization properties
por: Pamula, Melissa C., et al.
Publicado: (2016)

Interaction of microtubule depolymerizing agent indanocine with different human αβ tubulin isotypes
por: Kumbhar, Bajarang Vasant, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4ue0i7nr09oivpi9j2hiv2p4jm