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linkcomm: an R package for the generation, visualization, and analysis of link communities in networks of arbitrary size and type

Summary: An essential element when analysing the structure, function, and dynamics of biological networks is the identification of communities of related nodes. An algorithm proposed recently enhances this process by clustering the links between nodes, rather than the nodes themselves, thereby allow...

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Detalles Bibliográficos
Autores principales: Kalinka, Alex T., Tomancak, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129527/
https://www.ncbi.nlm.nih.gov/pubmed/21596792
http://dx.doi.org/10.1093/bioinformatics/btr311
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author Kalinka, Alex T.
Tomancak, Pavel
author_facet Kalinka, Alex T.
Tomancak, Pavel
author_sort Kalinka, Alex T.
collection PubMed
description Summary: An essential element when analysing the structure, function, and dynamics of biological networks is the identification of communities of related nodes. An algorithm proposed recently enhances this process by clustering the links between nodes, rather than the nodes themselves, thereby allowing each node to belong to multiple overlapping or nested communities. The R package ‘linkcomm’ implements this algorithm and extends it in several aspects: (i) the clustering algorithm handles networks that are weighted, directed, or both weighted and directed; (ii) several visualization methods are implemented that facilitate the representation of the link communities and their relationships; (iii) a suite of functions are included for the downstream analysis of the link communities including novel community-based measures of node centrality; (iv) the main algorithm is written in C++ and designed to handle networks of any size; and (v) several clustering methods are available for networks that can be handled in memory, and the number of communities can be adjusted by the user. Availability: The program is freely available from the Comprehensive R Archive Network (http://cran.r-project.org/) under the terms of the GNU General Public License (version 2 or later). Contact: kalinka@mpi-cbg.de Supplementary information: Supplementary data are available at Bioinformatics online.
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spelling pubmed-31295272011-07-06 linkcomm: an R package for the generation, visualization, and analysis of link communities in networks of arbitrary size and type Kalinka, Alex T. Tomancak, Pavel Bioinformatics Applications Note Summary: An essential element when analysing the structure, function, and dynamics of biological networks is the identification of communities of related nodes. An algorithm proposed recently enhances this process by clustering the links between nodes, rather than the nodes themselves, thereby allowing each node to belong to multiple overlapping or nested communities. The R package ‘linkcomm’ implements this algorithm and extends it in several aspects: (i) the clustering algorithm handles networks that are weighted, directed, or both weighted and directed; (ii) several visualization methods are implemented that facilitate the representation of the link communities and their relationships; (iii) a suite of functions are included for the downstream analysis of the link communities including novel community-based measures of node centrality; (iv) the main algorithm is written in C++ and designed to handle networks of any size; and (v) several clustering methods are available for networks that can be handled in memory, and the number of communities can be adjusted by the user. Availability: The program is freely available from the Comprehensive R Archive Network (http://cran.r-project.org/) under the terms of the GNU General Public License (version 2 or later). Contact: kalinka@mpi-cbg.de Supplementary information: Supplementary data are available at Bioinformatics online. Oxford University Press 2011-07-15 2011-05-19 /pmc/articles/PMC3129527/ /pubmed/21596792 http://dx.doi.org/10.1093/bioinformatics/btr311 Text en © The Author(s) 2011. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.5 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Note
Kalinka, Alex T.
Tomancak, Pavel
linkcomm: an R package for the generation, visualization, and analysis of link communities in networks of arbitrary size and type
title linkcomm: an R package for the generation, visualization, and analysis of link communities in networks of arbitrary size and type
title_full linkcomm: an R package for the generation, visualization, and analysis of link communities in networks of arbitrary size and type
title_fullStr linkcomm: an R package for the generation, visualization, and analysis of link communities in networks of arbitrary size and type
title_full_unstemmed linkcomm: an R package for the generation, visualization, and analysis of link communities in networks of arbitrary size and type
title_short linkcomm: an R package for the generation, visualization, and analysis of link communities in networks of arbitrary size and type
title_sort linkcomm: an r package for the generation, visualization, and analysis of link communities in networks of arbitrary size and type
topic Applications Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129527/
https://www.ncbi.nlm.nih.gov/pubmed/21596792
http://dx.doi.org/10.1093/bioinformatics/btr311
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