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Aromatase inhibitors and antiepileptic drugs: a computational systems biology analysis

BACKGROUND: The present study compares antiepileptic drugs and aromatase (CYP19) inhibitors for chemical and structural similarity. Human aromatase is well known as an important pharmacological target in anti-breast cancer therapy, but recent research demonstrates its role in epileptic seizures, as...

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Detalles Bibliográficos
Autores principales: Muftuoglu, Yagmur, Mustata, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129585/
https://www.ncbi.nlm.nih.gov/pubmed/21693043
http://dx.doi.org/10.1186/1477-7827-9-92