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GP88 (PC-Cell Derived Growth Factor, progranulin) stimulates proliferation and confers letrozole resistance to aromatase overexpressing breast cancer cells

BACKGROUND: Aromatase inhibitors (AI) that inhibit breast cancer cell growth by blocking estrogen synthesis have become the treatment of choice for post-menopausal women with estrogen receptor positive (ER(+)) breast cancer. However, some patients display de novo or acquired resistance to AI. Intera...

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Detalles Bibliográficos
Autores principales:	Abrhale, Tesfom, Brodie, Angela, Sabnis, Gauri, Macedo, Luciana, Tian, Changsheng, Yue, Binbin, Serrero, Ginette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129588/ https://www.ncbi.nlm.nih.gov/pubmed/21658239 http://dx.doi.org/10.1186/1471-2407-11-231

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