Wld(S) Reduces Paraquat-Induced Cytotoxicity via SIRT1 in Non-Neuronal Cells by Attenuating the Depletion of NAD

Wld(S) is a fusion protein with NAD synthesis activity, and has been reported to protect axonal and synaptic compartments of neurons from various mechanical, genetic and chemical insults. However, whether Wld(S) can protect non-neuronal cells against toxic chemicals is largely unknown. Here we found...

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Detalles Bibliográficos
Autores principales: Yu, Qiujing, Wang, Ting, Zhou, Xuexia, Wu, Jingxia, Chen, Xingmiao, Liu, Yang, Wu, Dongmei, Zhai, Qiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130051/
https://www.ncbi.nlm.nih.gov/pubmed/21750730
http://dx.doi.org/10.1371/journal.pone.0021770

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