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Nerve growth factor beta polypeptide (NGFB) genetic variability: association with the methadone dose required for effective maintenance treatment
Opioid addiction is a chronic disease with high genetic contribution and a large inter-individual variability in therapeutic response. The goal of this study was to identify pharmacodynamic factors that modulate methadone dose requirement. The neurotrophin family is involved in neural plasticity, le...
Autores principales: | Levran, Orna, Peles, Einat, Hamon, Sara, Randesi, Matthew, Zhao, Connie, Zhang, Bin, Adelson, Miriam, Kreek, Mary Jeanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130093/ https://www.ncbi.nlm.nih.gov/pubmed/21358750 http://dx.doi.org/10.1038/tpj.2011.6 |
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