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Pain Management in Patients with Cancer: Focus on Opioid Analgesics

Cancer pain is generally treated with pharmacological measures, relying on using opioids alone or in combination with adjuvant analgesics. Weak opioids are used for mild-to-moderate pain as monotherapy or in a combination with nonopioids. For patients with moderate-to-severe pain, strong opioids are...

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Detalles Bibliográficos
Autor principal: Leppert, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Current Science Inc. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130126/
https://www.ncbi.nlm.nih.gov/pubmed/21479998
http://dx.doi.org/10.1007/s11916-011-0201-7
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author Leppert, Wojciech
author_facet Leppert, Wojciech
author_sort Leppert, Wojciech
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description Cancer pain is generally treated with pharmacological measures, relying on using opioids alone or in combination with adjuvant analgesics. Weak opioids are used for mild-to-moderate pain as monotherapy or in a combination with nonopioids. For patients with moderate-to-severe pain, strong opioids are recommended as initial therapy rather than beginning treatment with weak opioids. Adjunctive therapy plays an important role in the treatment of cancer pain not fully responsive to opioids administered alone (ie, neuropathic, bone, and visceral colicky pain). Supportive drugs should be used wisely to prevent and treat opioids’ adverse effects. Understanding the pharmacokinetics, pharmacodynamics, interactions, and cautions with commonly used opioids can help determine appropriate opioid selection for individual cancer patients.
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spelling pubmed-31301262011-08-10 Pain Management in Patients with Cancer: Focus on Opioid Analgesics Leppert, Wojciech Curr Pain Headache Rep Article Cancer pain is generally treated with pharmacological measures, relying on using opioids alone or in combination with adjuvant analgesics. Weak opioids are used for mild-to-moderate pain as monotherapy or in a combination with nonopioids. For patients with moderate-to-severe pain, strong opioids are recommended as initial therapy rather than beginning treatment with weak opioids. Adjunctive therapy plays an important role in the treatment of cancer pain not fully responsive to opioids administered alone (ie, neuropathic, bone, and visceral colicky pain). Supportive drugs should be used wisely to prevent and treat opioids’ adverse effects. Understanding the pharmacokinetics, pharmacodynamics, interactions, and cautions with commonly used opioids can help determine appropriate opioid selection for individual cancer patients. Current Science Inc. 2011-04-12 2011 /pmc/articles/PMC3130126/ /pubmed/21479998 http://dx.doi.org/10.1007/s11916-011-0201-7 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Article
Leppert, Wojciech
Pain Management in Patients with Cancer: Focus on Opioid Analgesics
title Pain Management in Patients with Cancer: Focus on Opioid Analgesics
title_full Pain Management in Patients with Cancer: Focus on Opioid Analgesics
title_fullStr Pain Management in Patients with Cancer: Focus on Opioid Analgesics
title_full_unstemmed Pain Management in Patients with Cancer: Focus on Opioid Analgesics
title_short Pain Management in Patients with Cancer: Focus on Opioid Analgesics
title_sort pain management in patients with cancer: focus on opioid analgesics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130126/
https://www.ncbi.nlm.nih.gov/pubmed/21479998
http://dx.doi.org/10.1007/s11916-011-0201-7
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