Cargando…

T-bet-mediated differentiation of the activated CD8(+) T cell

The T-box transcription factor, T-bet promotes the differentiation of short-lived effector CD8(+) T cells at the expense of central memory cells. How T-bet mediates these effects, and whether they are directly caused by T-bet alone are unknown, because expression of T-bet requires stimulation of the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yeo, Crystal J J, Fearon, Douglas T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2011
Materias:	Cellular Immune Response
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130140/ https://www.ncbi.nlm.nih.gov/pubmed/21182077 http://dx.doi.org/10.1002/eji.201040873

Ejemplares similares

CD8 exerts differential effects on the deployment of cytotoxic T lymphocyte effector functions
por: Laugel, Bruno, et al.
Publicado: (2007)

Tumor-specific CD4(+) T cells maintain effector and memory tumor-specific CD8(+) T cells
por: Church, Sarah E, et al.
Publicado: (2014)

Crosstalk between human DC subsets promotes antibacterial activity and CD8(+) T-cell stimulation in response to bacille Calmette-Guérin
por: Lozza, Laura, et al.
Publicado: (2014)

TGF‐β induces the differentiation of human CXCL13‐producing CD4(+) T cells
por: Kobayashi, Shio, et al.
Publicado: (2015)

Activated CD4(+) T cells enter the splenic T-cell zone and induce autoantibody-producing germinal centers through bystander activation
por: Banczyk, David, et al.
Publicado: (2014)

PI3Kγ kinase activity is required for optimal T-cell activation and differentiation
por: Ladygina, Nadia, et al.
Publicado: (2013)

Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy
por: Kropf, Pascale, et al.
Publicado: (2007)

The role of ICOS in the development of CD4 T cell help and the reactivation of memory T cells
por: Mahajan, Simmi, et al.
Publicado: (2007)

Antigen targeting reveals splenic CD169(+) macrophages as promoters of germinal center B‐cell responses
por: Veninga, Henrike, et al.
Publicado: (2015)

CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner
por: Afzali, Behdad, et al.
Publicado: (2013)

TLR-mediated stimulation of APC: Distinct cytokine responses of B cells and dendritic cells
por: Barr, Tom A, et al.
Publicado: (2007)

A distinct subset of human NK cells expressing HLA-DR expand in response to IL-2 and can aid immune responses to BCG
por: Evans, J Henry, et al.
Publicado: (2011)

Resolving Salmonella infection reveals dynamic and persisting changes in murine bone marrow progenitor cell phenotype and function
por: Ross, Ewan A, et al.
Publicado: (2014)

Cytip regulates dendritic-cell function in contact hypersensitivity
por: Heib, Valeska, et al.
Publicado: (2012)

Bob1 limits cellular frequency of T‐follicular helper cells
por: Yamashita, Keiji, et al.
Publicado: (2016)

Cardiomyocytes display low mitochondrial priming and are highly resistant toward cytotoxic T‐cell killing
por: Zheng, Xiang, et al.
Publicado: (2016)

Fibroblasts from different sites may promote or inhibit recruitment of flowing lymphocytes by endothelial cells
por: McGettrick, Helen M, et al.
Publicado: (2009)

Relb acts downstream of medullary thymic epithelial stem cells and is essential for the emergence of RANK(+) medullary epithelial progenitors
por: Baik, Song, et al.
Publicado: (2016)

IL-10-dependent partial refractoriness to Toll-like receptor stimulation modulates gut mucosal dendritic cell function
por: Monteleone, Ivan, et al.
Publicado: (2008)

ST2 deletion enhances innate and acquired immunity to murine mammary carcinoma
por: Jovanovic, Ivan, et al.
Publicado: (2011)

Targeting DNGR-1 (CLEC9A) with antibody/MUC1 peptide conjugates as a vaccine for carcinomas
por: Picco, Gianfranco, et al.
Publicado: (2014)

The expression of mouse CLEC‐2 on leucocyte subsets varies according to their anatomical location and inflammatory state
por: Lowe, Kate L., et al.
Publicado: (2015)

T lymphocytes need less than 3 min to discriminate between peptide MHCs with similar TCR-binding parameters
por: Brodovitch, Alexandre, et al.
Publicado: (2015)

Dynamic spatio‐temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla
por: Mayer, Carlos E., et al.
Publicado: (2016)

An evolutionarily conserved mutual interdependence between Aire and microRNAs in promiscuous gene expression
por: Ucar, Olga, et al.
Publicado: (2013)

Differential Immunodominance Hierarchy of CD8(+) T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection
por: Adland, Emily, et al.
Publicado: (2018)

STING Ligand-Mediated Priming of Functional CD8(+) T Cells Specific for HIV-1-Protective Epitopes from Naive T Cells
por: Kuse, Nozomi, et al.
Publicado: (2021)

HIV Infection Functionally Impairs Mycobacterium tuberculosis-Specific CD4 and CD8 T-Cell Responses
por: Amelio, Patrizia, et al.
Publicado: (2019)

Characterization of Human CD8 T Cell Responses in Dengue Virus-Infected Patients from India
por: Chandele, Anmol, et al.
Publicado: (2016)

Tumor Necrosis Factor-Mediated Survival of CD169(+) Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection
por: Shinde, Prashant V., et al.
Publicado: (2018)

Curtailed T‐cell activation curbs effector differentiation and generates CD8(+) T cells with a naturally‐occurring memory stem cell phenotype
por: Zanon, Veronica, et al.
Publicado: (2017)

Polypyrimidine tract binding protein 1 regulates the activation of mouse CD8 T cells
por: D'Angeli, Vanessa, et al.
Publicado: (2022)

CD161(++)CD8(+) T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner
por: Ussher, James E, et al.
Publicado: (2014)

CD28 and CD57 define four populations with distinct phenotypic properties within human CD8(+) T cells
por: Pangrazzi, Luca, et al.
Publicado: (2019)

CD8(+) Treg cells suppress CD8(+) T cell-responses by IL-10-dependent mechanism during H5N1 influenza virus infection
por: Zou, Qiang, et al.
Publicado: (2014)

Memory CD8(+) T cells upregulate glycolysis and effector functions under limiting oxygen conditions
por: Beumer‐Chuwonpad, Ammarina, et al.
Publicado: (2022)

Bromodomain inhibitor I‐BET151 suppresses immune responses during fungal–immune interaction
por: Domínguez‐Andrés, Jorge, et al.
Publicado: (2019)

Egr2 and 3 Inhibit T-bet–Mediated IFN-γ Production in T Cells
por: Singh, Randeep, et al.
Publicado: (2017)

Cellular Gene Modulation of HIV-Infected CD4 T Cells in Response to Serial Treatment with the Histone Deacetylase Inhibitor Vorinostat
por: Maxwell, Jill W., et al.
Publicado: (2020)

Nonhuman TRIM5 Variants Enhance Recognition of HIV-1-Infected Cells by CD8(+) T Cells
por: Jimenez-Moyano, Esther, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_h1ijpsr5iajvsjq9t9c6o54n93