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Bile retinoids imprint intestinal CD103(+) dendritic cells with the ability to generate gut-tropic T cells
Small intestinal lamina propria (SI-LP) CD103(+) dendritic cells (DCs) are imprinted with an ability to metabolize vitamin A (retinol), a property underlying their enhanced capacity to induce the gut-homing receptors CC chemokine receptor-9 and α4β7 on responding T cells. In this study, we demonstra...
Autores principales: | Jaensson-Gyllenbäck, E, Kotarsky, K, Zapata, F, Persson, E K, Gundersen, T E, Blomhoff, R, Agace, W W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130189/ https://www.ncbi.nlm.nih.gov/pubmed/21289617 http://dx.doi.org/10.1038/mi.2010.91 |
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