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Identification of altered function alleles that affect Bacillus subtilis PerR metal ion selectivity

Bacillus subtilis PerR is a Fur family repressor that senses hydrogen peroxide by metal-catalyzed oxidation. PerR contains a structural Zn(II) ion (Site 1) and a regulatory metal binding site (Site 2) that, upon association with either Mn(II) or Fe(II), allosterically activates DNA binding. In addit...

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Detalles Bibliográficos
Autores principales:	Ma, Zhen, Lee, Jin-Won, Helmann, John D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130269/ https://www.ncbi.nlm.nih.gov/pubmed/21398634 http://dx.doi.org/10.1093/nar/gkr095

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