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Characterization of PvuRts1I endonuclease as a tool to investigate genomic 5–hydroxymethylcytosine
In mammalian genomes a sixth base, 5-hydroxymethylcytosine ((hm)C), is generated by enzymatic oxidation of 5-methylcytosine ((m)C). This discovery has raised fundamental questions about the functional relevance of (hm)C in mammalian genomes. Due to their very similar chemical structure, discriminati...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130283/ https://www.ncbi.nlm.nih.gov/pubmed/21378122 http://dx.doi.org/10.1093/nar/gkr118 |