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A method for counting PCR template molecules with application to next-generation sequencing

Amplification by polymerase chain reaction is often used in the preparation of template DNA molecules for next-generation sequencing. Amplification increases the number of available molecules for sequencing but changes the representation of the template molecules in the amplified product and introdu...

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Detalles Bibliográficos
Autores principales: Casbon, James A., Osborne, Robert J., Brenner, Sydney, Lichtenstein, Conrad P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130290/
https://www.ncbi.nlm.nih.gov/pubmed/21490082
http://dx.doi.org/10.1093/nar/gkr217

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