Thrombospondin 1 in hypoxia-conditioned media blocks the growth of human microvascular endothelial cells and is increased in systemic sclerosis tissues

BACKGROUND: Systemic sclerosis (SSc) is a chronic inflammatory autoimmune disease characterised by vascular dysfunction and damage, excess collagen deposition and subsequent organ manifestations. Vasculopathy is an early feature of the disease which leads to a chronic hypoxic environment in the tiss...

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Detalles Bibliográficos
Autores principales: Morgan-Rowe, Luke, Nikitorowicz, Joanna, Shiwen, Xu, Leask, Andrew, Tsui, Janice, Abraham, David, Stratton, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130666/
https://www.ncbi.nlm.nih.gov/pubmed/21635730
http://dx.doi.org/10.1186/1755-1536-4-13

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