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Modularity-based credible prediction of disease genes and detection of disease subtypes on the phenotype-gene heterogeneous network

BACKGROUND: Protein-protein interaction networks and phenotype similarity information have been synthesized together to discover novel disease-causing genes. Genetic or phenotypic similarities are manifested as certain modularity properties in a phenotype-gene heterogeneous network consisting of the...

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Detalles Bibliográficos
Autores principales: Yao, Xin, Hao, Han, Li, Yanda, Li, Shao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130676/
https://www.ncbi.nlm.nih.gov/pubmed/21599985
http://dx.doi.org/10.1186/1752-0509-5-79