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Modularity-based credible prediction of disease genes and detection of disease subtypes on the phenotype-gene heterogeneous network
BACKGROUND: Protein-protein interaction networks and phenotype similarity information have been synthesized together to discover novel disease-causing genes. Genetic or phenotypic similarities are manifested as certain modularity properties in a phenotype-gene heterogeneous network consisting of the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130676/ https://www.ncbi.nlm.nih.gov/pubmed/21599985 http://dx.doi.org/10.1186/1752-0509-5-79 |