Pleiotrophin over-expression provides trophic support to dopaminergic neurons in parkinsonian rats

BACKGROUND: Pleiotrophin is known to promote the survival and differentiation of dopaminergic neurons in vitro and is up-regulated in the substantia nigra of Parkinson's disease patients. To establish whether pleiotrophin has a trophic effect on nigrostriatal dopaminergic neurons in vivo, we in...

Descripción completa

Detalles Bibliográficos
Autores principales: Taravini, Irene RE, Chertoff, Mariela, Cafferata, Eduardo G, Courty, José, Murer, Mario G, Pitossi, Fernando J, Gershanik, Oscar S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130680/
https://www.ncbi.nlm.nih.gov/pubmed/21649894
http://dx.doi.org/10.1186/1750-1326-6-40

Ejemplares similares

Ejemplares similares