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PIK3CA-mediated PI3-kinase signalling is essential for HPV-induced transformation in vitro
BACKGROUND: High-risk human papillomavirus (hrHPV) infections are causally related to cervical cancer development. The additional (epi)genetic alterations driving malignant transformation of hrHPV-infected cells however, are not yet fully elucidated. In this study we experimentally assessed the role...
Autores principales: | Henken, Florianne E, Banerjee, N Sanjib, Snijders, Peter JF, Meijer, Chris JLM, De-Castro Arce, Johanna, Rösl, Frank, Broker, Thomas R, Chow, Louise T, Steenbergen, Renske DM |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130697/ https://www.ncbi.nlm.nih.gov/pubmed/21663621 http://dx.doi.org/10.1186/1476-4598-10-71 |
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