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COX-2 gene expression in colon cancer tissue related to regulating factors and promoter methylation status

BACKGROUND: Increased cyclooxygenase activity promotes progression of colorectal cancer, but the mechanisms behind COX-2 induction remain elusive. This study was therefore aimed to define external cell signaling and transcription factors relating to high COX-2 expression in colon cancer tissue. METH...

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Detalles Bibliográficos
Autores principales:	Asting, Annika Gustafsson, Carén, Helena, Andersson, Marianne, Lönnroth, Christina, Lagerstedt, Kristina, Lundholm, Kent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130705/ https://www.ncbi.nlm.nih.gov/pubmed/21668942 http://dx.doi.org/10.1186/1471-2407-11-238

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