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A Generic Program for Multistate Protein Design

Some protein design tasks cannot be modeled by the traditional single state design strategy of finding a sequence that is optimal for a single fixed backbone. Such cases require multistate design, where a single sequence is threaded onto multiple backbones (states) and evaluated for its strengths an...

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Detalles Bibliográficos
Autores principales: Leaver-Fay, Andrew, Jacak, Ron, Stranges, P. Benjamin, Kuhlman, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130737/
https://www.ncbi.nlm.nih.gov/pubmed/21754981
http://dx.doi.org/10.1371/journal.pone.0020937