Increased IKKα Expression in the Basal Layer of the Epidermis of Transgenic Mice Enhances the Malignant Potential of Skin Tumors

Non-melanoma skin cancer is the most frequent type of cancer in humans. In this study we demonstrate that elevated IKKα expression in murine epidermis increases the malignancy potential of skin tumors. We describe the generation of transgenic mice overexpressing IKKα in the basal, proliferative laye...

Descripción completa

Detalles Bibliográficos
Autores principales: Alameda, Josefa P., Moreno-Maldonado, Rodolfo, Fernández-Aceñero, M. Jesús, Navarro, Manuel, Page, Angustias, Jorcano, José L., Bravo, Ana, Ramírez, Ángel, Casanova, M. Llanos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130791/
https://www.ncbi.nlm.nih.gov/pubmed/21755017
http://dx.doi.org/10.1371/journal.pone.0021984

Ejemplares similares

Ejemplares similares