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Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation
Synaptotagmin-1 triggers Ca(2+)-sensitive, rapid neurotransmitter release by promoting the interaction of SNARE proteins between the synaptic vesicles and the plasma membrane. How synaptotagmin-1 promotes this interaction is controversial, and the massive increase in membrane fusion efficiency of Ca...
Autores principales: | van den Bogaart, Geert, Thutupalli, Shashi, Risselada, Jelger H., Meyenberg, Karsten, Holt, Matthew, Riedel, Dietmar, Diederichsen, Ulf, Herminghaus, Stephan, Grubmüller, Helmut, Jahn, Reinhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130798/ https://www.ncbi.nlm.nih.gov/pubmed/21642968 http://dx.doi.org/10.1038/nsmb.2061 |
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