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Barriers to Non-Viral Vector-Mediated Gene Delivery in the Nervous System
Efficient methods for cell line transfection are well described, but, for primary neurons, a high-yield method different from those relying on viral vectors is lacking. Viral transfection has several drawbacks, such as the complexity of vector preparation, safety concerns, and the generation of immu...
Autores principales: | Pérez-Martínez, Francisco C., Guerra, Javier, Posadas, Inmaculada, Ceña, Valentín |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130907/ https://www.ncbi.nlm.nih.gov/pubmed/21225319 http://dx.doi.org/10.1007/s11095-010-0364-7 |
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