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Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery
BACKGROUND: The purpose of this review was to provide a critical appraisal of the literature supporting the efficacy of ophthalmic ketorolac (Acuvail(®)) in the treatment of pain and inflammation after cataract surgery. METHODS: Literature search and expert opinion of the authors. RESULTS: Recent st...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130912/ https://www.ncbi.nlm.nih.gov/pubmed/21750608 http://dx.doi.org/10.2147/OPTH.S7633 |
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author | Reddy, Rahul Kim, Stephen Jae |
author_facet | Reddy, Rahul Kim, Stephen Jae |
author_sort | Reddy, Rahul |
collection | PubMed |
description | BACKGROUND: The purpose of this review was to provide a critical appraisal of the literature supporting the efficacy of ophthalmic ketorolac (Acuvail(®)) in the treatment of pain and inflammation after cataract surgery. METHODS: Literature search and expert opinion of the authors. RESULTS: Recent studies indicate greater intraocular drug levels in the anterior chamber and iris-ciliary body after topical application of Acuvail in comparison with older formulations of ketorolac. A large randomized, multicenter, placebo-controlled study demonstrated significantly less inflammation and pain after cataract surgery using Acuvail. CONCLUSION: Acuvail appears to be effective in reducing post-cataract surgery pain and inflammation. |
format | Online Article Text |
id | pubmed-3130912 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-31309122011-07-12 Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery Reddy, Rahul Kim, Stephen Jae Clin Ophthalmol Review BACKGROUND: The purpose of this review was to provide a critical appraisal of the literature supporting the efficacy of ophthalmic ketorolac (Acuvail(®)) in the treatment of pain and inflammation after cataract surgery. METHODS: Literature search and expert opinion of the authors. RESULTS: Recent studies indicate greater intraocular drug levels in the anterior chamber and iris-ciliary body after topical application of Acuvail in comparison with older formulations of ketorolac. A large randomized, multicenter, placebo-controlled study demonstrated significantly less inflammation and pain after cataract surgery using Acuvail. CONCLUSION: Acuvail appears to be effective in reducing post-cataract surgery pain and inflammation. Dove Medical Press 2011 2011-06-03 /pmc/articles/PMC3130912/ /pubmed/21750608 http://dx.doi.org/10.2147/OPTH.S7633 Text en © 2011 Reddy and Kim, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Review Reddy, Rahul Kim, Stephen Jae Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery |
title | Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery |
title_full | Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery |
title_fullStr | Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery |
title_full_unstemmed | Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery |
title_short | Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery |
title_sort | critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130912/ https://www.ncbi.nlm.nih.gov/pubmed/21750608 http://dx.doi.org/10.2147/OPTH.S7633 |
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