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Antimicrobial Traits of Tea- and Cranberry-Derived Polyphenols against Streptococcus mutans

There are over 750 species of bacteria that inhabit the human oral cavity, but only a small fraction of those are attributed to causing plaque-related diseases such as caries. Streptococcus mutans is accepted as the main cariogenic agent and there is substantial knowledge regarding the specific viru...

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Detalles Bibliográficos
Autores principales: Yoo, S., Murata, R.M., Duarte, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130978/
https://www.ncbi.nlm.nih.gov/pubmed/21720161
http://dx.doi.org/10.1159/000329181
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author Yoo, S.
Murata, R.M.
Duarte, S.
author_facet Yoo, S.
Murata, R.M.
Duarte, S.
author_sort Yoo, S.
collection PubMed
description There are over 750 species of bacteria that inhabit the human oral cavity, but only a small fraction of those are attributed to causing plaque-related diseases such as caries. Streptococcus mutans is accepted as the main cariogenic agent and there is substantial knowledge regarding the specific virulence factors that render the organism a pathogen. There has been rising interest in alternative, target-specific treatment options as opposed to nonspecific mechanical plaque removal or application of broad-spectrum antibacterials that are currently in use. The impact of diet on oral health is undeniable, and this is directly observable in populations that consume high quantities of polyphenol-rich foods or beverages. Such populations have low caries incidence and better overall oral health. Camellia sinensis, the plant from which various forms of tea are derived, and Vaccinium macrocarpon (American cranberry fruit) have received notable attention both for their prevalence in the human diet as well as for their unique composition of polyphenols. The biologically active constituents of these plants have demonstrated potent enzyme-inhibitory properties without being bactericidal, a key quality that is important in developing therapies that will not cause microorganisms to develop resistance. The aim of this review is to consider studies that have investigated the feasibility of tea, cranberry, and other select plant derivatives as a potential basis for alternative therapeutic agents against Streptococcus mutans and to evaluate their current and future clinical relevance.
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spelling pubmed-31309782013-08-29 Antimicrobial Traits of Tea- and Cranberry-Derived Polyphenols against Streptococcus mutans Yoo, S. Murata, R.M. Duarte, S. Caries Res Review There are over 750 species of bacteria that inhabit the human oral cavity, but only a small fraction of those are attributed to causing plaque-related diseases such as caries. Streptococcus mutans is accepted as the main cariogenic agent and there is substantial knowledge regarding the specific virulence factors that render the organism a pathogen. There has been rising interest in alternative, target-specific treatment options as opposed to nonspecific mechanical plaque removal or application of broad-spectrum antibacterials that are currently in use. The impact of diet on oral health is undeniable, and this is directly observable in populations that consume high quantities of polyphenol-rich foods or beverages. Such populations have low caries incidence and better overall oral health. Camellia sinensis, the plant from which various forms of tea are derived, and Vaccinium macrocarpon (American cranberry fruit) have received notable attention both for their prevalence in the human diet as well as for their unique composition of polyphenols. The biologically active constituents of these plants have demonstrated potent enzyme-inhibitory properties without being bactericidal, a key quality that is important in developing therapies that will not cause microorganisms to develop resistance. The aim of this review is to consider studies that have investigated the feasibility of tea, cranberry, and other select plant derivatives as a potential basis for alternative therapeutic agents against Streptococcus mutans and to evaluate their current and future clinical relevance. S. Karger AG 2011-09 2011-06-30 /pmc/articles/PMC3130978/ /pubmed/21720161 http://dx.doi.org/10.1159/000329181 Text en Copyright © 2011 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Review
Yoo, S.
Murata, R.M.
Duarte, S.
Antimicrobial Traits of Tea- and Cranberry-Derived Polyphenols against Streptococcus mutans
title Antimicrobial Traits of Tea- and Cranberry-Derived Polyphenols against Streptococcus mutans
title_full Antimicrobial Traits of Tea- and Cranberry-Derived Polyphenols against Streptococcus mutans
title_fullStr Antimicrobial Traits of Tea- and Cranberry-Derived Polyphenols against Streptococcus mutans
title_full_unstemmed Antimicrobial Traits of Tea- and Cranberry-Derived Polyphenols against Streptococcus mutans
title_short Antimicrobial Traits of Tea- and Cranberry-Derived Polyphenols against Streptococcus mutans
title_sort antimicrobial traits of tea- and cranberry-derived polyphenols against streptococcus mutans
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130978/
https://www.ncbi.nlm.nih.gov/pubmed/21720161
http://dx.doi.org/10.1159/000329181
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