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CD1a-autoreactive T cells are a normal component of the human αβ T cell repertoire

CD1 activates T cells, but the functions and size of possible human T cell repertoires recognizing each of the CD1 antigen presenting molecules remain unknown. Using an experimental system that bypasses major histocompatibility complex (MHC) restriction and the requirement for defined antigens, we f...

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Detalles Bibliográficos
Autores principales: de Jong, Annemieke, Peña-Cruz, Victor, Cheng, Tan-Yun, Clark, Rachael A., Van Rhijn, Ildiko, Moody, D. Branch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131223/
https://www.ncbi.nlm.nih.gov/pubmed/21037579
http://dx.doi.org/10.1038/ni.1956