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Programmed Death (PD)-1-Deficient Mice Are Extremely Sensitive to Murine Hepatitis Virus Strain-3 (MHV-3) Infection

The inhibitory receptor programmed death-1 (PD-1) has the capacity to maintain peripheral tolerance and limit immunopathological damage; however, its precise role in fulminant viral hepatitis (FH) has yet to be described. Here, we investigated the functional mechanisms of PD-1 as related to FH patho...

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Detalles Bibliográficos
Autores principales:	Chen, Yongwen, Wu, Shengxi, Guo, Guoning, Fei, Lei, Guo, Sheng, Yang, Chengying, Fu, Xiaolan, Wu, Yuzhang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131267/ https://www.ncbi.nlm.nih.gov/pubmed/21750671 http://dx.doi.org/10.1371/journal.ppat.1001347

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