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NatF Contributes to an Evolutionary Shift in Protein N-Terminal Acetylation and Is Important for Normal Chromosome Segregation
N-terminal acetylation (N-Ac) is a highly abundant eukaryotic protein modification. Proteomics revealed a significant increase in the occurrence of N-Ac from lower to higher eukaryotes, but evidence explaining the underlying molecular mechanism(s) is currently lacking. We first analysed protein N-te...
Autores principales: | Van Damme, Petra, Hole, Kristine, Pimenta-Marques, Ana, Helsens, Kenny, Vandekerckhove, Joël, Martinho, Rui G., Gevaert, Kris, Arnesen, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131286/ https://www.ncbi.nlm.nih.gov/pubmed/21750686 http://dx.doi.org/10.1371/journal.pgen.1002169 |
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