Interactions between Glucocorticoid Treatment and Cis-Regulatory Polymorphisms Contribute to Cellular Response Phenotypes

Glucocorticoids (GCs) mediate physiological responses to environmental stress and are commonly used as pharmaceuticals. GCs act primarily through the GC receptor (GR, a transcription factor). Despite their clear biomedical importance, little is known about the genetic architecture of variation in GC...

Descripción completa

Detalles Bibliográficos
Autores principales: Maranville, Joseph C., Luca, Francesca, Richards, Allison L., Wen, Xiaoquan, Witonsky, David B., Baxter, Shaneen, Stephens, Matthew, Di Rienzo, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131293/
https://www.ncbi.nlm.nih.gov/pubmed/21750684
http://dx.doi.org/10.1371/journal.pgen.1002162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131293/
https://www.ncbi.nlm.nih.gov/pubmed/21750684
http://dx.doi.org/10.1371/journal.pgen.1002162

Ejemplares similares