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Increased abundance of the adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif (APPL1) in patients with obesity and type 2 diabetes: evidence for altered adiponectin signalling

AIMS/HYPOTHESIS: The adiponectin signalling pathway is largely unknown, but recently the adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif (APPL1), has been shown to interact directly with adiponectin receptor (ADIPOR)1. APPL1 is present i...

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Detalles Bibliográficos
Autores principales:	Holmes, R. M., Yi, Z., De Filippis, E., Berria, R., Shahani, S., Sathyanarayana, P., Sherman, V., Fujiwara, K., Meyer, C., Christ-Roberts, C., Hwang, H., Finlayson, J., Dong, L. Q., Mandarino, L. J., Bajaj, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131511/ https://www.ncbi.nlm.nih.gov/pubmed/21562756 http://dx.doi.org/10.1007/s00125-011-2173-x

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