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Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications
The autonomic nervous system interacts in the pathophysiology of heart failure. Dysfunction of the sympathetic nervous system has been identified as an important prognostic marker in patients with chronic heart failure. At present, cardiac sympathetic nerve imaging with 123-iodine metaiodobenzylguan...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Bentham Science Publishers Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131714/ https://www.ncbi.nlm.nih.gov/pubmed/22294973 http://dx.doi.org/10.2174/157340311795677725 |
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author | J. Boogers, Mark E. Veltman, Caroline J. Bax, Jeroen |
author_facet | J. Boogers, Mark E. Veltman, Caroline J. Bax, Jeroen |
author_sort | J. Boogers, Mark |
collection | PubMed |
description | The autonomic nervous system interacts in the pathophysiology of heart failure. Dysfunction of the sympathetic nervous system has been identified as an important prognostic marker in patients with chronic heart failure. At present, cardiac sympathetic nerve imaging with 123-iodine metaiodobenzylguanidine [123-I MIBG] has been employed most frequently for the assessment of cardiac sympathetic innervation and activation pattern. The majority of studies have shown that cardiac sympathetic dysfunction as assessed with 123-I MIBG imaging is a powerful predictor for heart failure mortality and morbidity. Additionally, 123-I MIBG imaging can be used for prediction of potentially lethal ventricular tachyarrhythmias in heart failure patients. At present however, the lack of standardization of 123-I MIBG imaging procedures represents an evident issue. Standardized criteria on the use of 123-I MIBG imaging will further strengthen the clinical use of 123-I MIBG imaging in heart failure patients. |
format | Online Article Text |
id | pubmed-3131714 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Bentham Science Publishers Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-31317142012-02-01 Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications J. Boogers, Mark E. Veltman, Caroline J. Bax, Jeroen Curr Cardiol Rev Article The autonomic nervous system interacts in the pathophysiology of heart failure. Dysfunction of the sympathetic nervous system has been identified as an important prognostic marker in patients with chronic heart failure. At present, cardiac sympathetic nerve imaging with 123-iodine metaiodobenzylguanidine [123-I MIBG] has been employed most frequently for the assessment of cardiac sympathetic innervation and activation pattern. The majority of studies have shown that cardiac sympathetic dysfunction as assessed with 123-I MIBG imaging is a powerful predictor for heart failure mortality and morbidity. Additionally, 123-I MIBG imaging can be used for prediction of potentially lethal ventricular tachyarrhythmias in heart failure patients. At present however, the lack of standardization of 123-I MIBG imaging procedures represents an evident issue. Standardized criteria on the use of 123-I MIBG imaging will further strengthen the clinical use of 123-I MIBG imaging in heart failure patients. Bentham Science Publishers Ltd 2011-02 /pmc/articles/PMC3131714/ /pubmed/22294973 http://dx.doi.org/10.2174/157340311795677725 Text en © 2011 Bentham Science Publishers Ltd. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article J. Boogers, Mark E. Veltman, Caroline J. Bax, Jeroen Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications |
title | Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications |
title_full | Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications |
title_fullStr | Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications |
title_full_unstemmed | Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications |
title_short | Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications |
title_sort | cardiac autonomic nervous system in heart failure: imaging technique and clinical implications |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131714/ https://www.ncbi.nlm.nih.gov/pubmed/22294973 http://dx.doi.org/10.2174/157340311795677725 |
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