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Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications

The autonomic nervous system interacts in the pathophysiology of heart failure. Dysfunction of the sympathetic nervous system has been identified as an important prognostic marker in patients with chronic heart failure. At present, cardiac sympathetic nerve imaging with 123-iodine metaiodobenzylguan...

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Detalles Bibliográficos
Autores principales: J. Boogers, Mark, E. Veltman, Caroline, J. Bax, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131714/
https://www.ncbi.nlm.nih.gov/pubmed/22294973
http://dx.doi.org/10.2174/157340311795677725
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author J. Boogers, Mark
E. Veltman, Caroline
J. Bax, Jeroen
author_facet J. Boogers, Mark
E. Veltman, Caroline
J. Bax, Jeroen
author_sort J. Boogers, Mark
collection PubMed
description The autonomic nervous system interacts in the pathophysiology of heart failure. Dysfunction of the sympathetic nervous system has been identified as an important prognostic marker in patients with chronic heart failure. At present, cardiac sympathetic nerve imaging with 123-iodine metaiodobenzylguanidine [123-I MIBG] has been employed most frequently for the assessment of cardiac sympathetic innervation and activation pattern. The majority of studies have shown that cardiac sympathetic dysfunction as assessed with 123-I MIBG imaging is a powerful predictor for heart failure mortality and morbidity. Additionally, 123-I MIBG imaging can be used for prediction of potentially lethal ventricular tachyarrhythmias in heart failure patients. At present however, the lack of standardization of 123-I MIBG imaging procedures represents an evident issue. Standardized criteria on the use of 123-I MIBG imaging will further strengthen the clinical use of 123-I MIBG imaging in heart failure patients.
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spelling pubmed-31317142012-02-01 Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications J. Boogers, Mark E. Veltman, Caroline J. Bax, Jeroen Curr Cardiol Rev Article The autonomic nervous system interacts in the pathophysiology of heart failure. Dysfunction of the sympathetic nervous system has been identified as an important prognostic marker in patients with chronic heart failure. At present, cardiac sympathetic nerve imaging with 123-iodine metaiodobenzylguanidine [123-I MIBG] has been employed most frequently for the assessment of cardiac sympathetic innervation and activation pattern. The majority of studies have shown that cardiac sympathetic dysfunction as assessed with 123-I MIBG imaging is a powerful predictor for heart failure mortality and morbidity. Additionally, 123-I MIBG imaging can be used for prediction of potentially lethal ventricular tachyarrhythmias in heart failure patients. At present however, the lack of standardization of 123-I MIBG imaging procedures represents an evident issue. Standardized criteria on the use of 123-I MIBG imaging will further strengthen the clinical use of 123-I MIBG imaging in heart failure patients. Bentham Science Publishers Ltd 2011-02 /pmc/articles/PMC3131714/ /pubmed/22294973 http://dx.doi.org/10.2174/157340311795677725 Text en © 2011 Bentham Science Publishers Ltd. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
J. Boogers, Mark
E. Veltman, Caroline
J. Bax, Jeroen
Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications
title Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications
title_full Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications
title_fullStr Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications
title_full_unstemmed Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications
title_short Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications
title_sort cardiac autonomic nervous system in heart failure: imaging technique and clinical implications
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131714/
https://www.ncbi.nlm.nih.gov/pubmed/22294973
http://dx.doi.org/10.2174/157340311795677725
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