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Treatment of active lupus nephritis with the novel immunosuppressant 15-deoxyspergualin: an open-label dose escalation study

INTRODUCTION: As the immunosuppressive potency of 15-deoxyspergualin (DSG) has been shown in the therapy of renal transplant rejection and Wegener's granulomatosis, the intention of this study was to evaluate the safety of DSG in the therapy of lupus nephritis (LN). METHODS: Patients with histo...

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Detalles Bibliográficos
Autores principales: Lorenz, Hanns-Martin, Schmitt, Wilhelm H, Tesar, Vladimir, Müller-Ladner, Ulf, Tarner, Ingo, Hauser, Ingeborg A, Hiepe, Falk, Alexander, Tobias, Woehling, Heike, Nemoto, Kyuichi, Heinzel, Peter A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132014/
https://www.ncbi.nlm.nih.gov/pubmed/21356124
http://dx.doi.org/10.1186/ar3268