Novel autoantibodies and clinical phenotypes in adult and juvenile myositis

Autoantibodies targeting intracellular proteins involved in key processes are detected in patients with idiopathic inflammatory myopathies. These myositisspecific autoantibodies have been increasingly demonstrated to correlate with distinct clinical phenotypes within the myositis spectrum. This revi...

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Detalles Bibliográficos
Autores principales: Betteridge, Zoe E, Gunawardena, Harsha, McHugh, Neil J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132021/
https://www.ncbi.nlm.nih.gov/pubmed/21457520
http://dx.doi.org/10.1186/ar3275
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author Betteridge, Zoe E
Gunawardena, Harsha
McHugh, Neil J
author_facet Betteridge, Zoe E
Gunawardena, Harsha
McHugh, Neil J
author_sort Betteridge, Zoe E
collection PubMed
description Autoantibodies targeting intracellular proteins involved in key processes are detected in patients with idiopathic inflammatory myopathies. These myositisspecific autoantibodies have been increasingly demonstrated to correlate with distinct clinical phenotypes within the myositis spectrum. This review highlights the clinical associations of the myositisspecific autoantibodies, with particular attention to the recently identified and characterized novel myositis autoantibodies: p155/140, p140 (MJ), CADM-140 (MDA5), SAE, and 200/100.
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spelling pubmed-31320212011-09-18 Novel autoantibodies and clinical phenotypes in adult and juvenile myositis Betteridge, Zoe E Gunawardena, Harsha McHugh, Neil J Arthritis Res Ther Review Autoantibodies targeting intracellular proteins involved in key processes are detected in patients with idiopathic inflammatory myopathies. These myositisspecific autoantibodies have been increasingly demonstrated to correlate with distinct clinical phenotypes within the myositis spectrum. This review highlights the clinical associations of the myositisspecific autoantibodies, with particular attention to the recently identified and characterized novel myositis autoantibodies: p155/140, p140 (MJ), CADM-140 (MDA5), SAE, and 200/100. BioMed Central 2011 2011-03-18 /pmc/articles/PMC3132021/ /pubmed/21457520 http://dx.doi.org/10.1186/ar3275 Text en Copyright ©2011 BioMed Central Ltd
spellingShingle Review
Betteridge, Zoe E
Gunawardena, Harsha
McHugh, Neil J
Novel autoantibodies and clinical phenotypes in adult and juvenile myositis
title Novel autoantibodies and clinical phenotypes in adult and juvenile myositis
title_full Novel autoantibodies and clinical phenotypes in adult and juvenile myositis
title_fullStr Novel autoantibodies and clinical phenotypes in adult and juvenile myositis
title_full_unstemmed Novel autoantibodies and clinical phenotypes in adult and juvenile myositis
title_short Novel autoantibodies and clinical phenotypes in adult and juvenile myositis
title_sort novel autoantibodies and clinical phenotypes in adult and juvenile myositis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132021/
https://www.ncbi.nlm.nih.gov/pubmed/21457520
http://dx.doi.org/10.1186/ar3275
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