Cargando…

Comparative efficacy of a secretory phospholipase A(2 )inhibitor with conventional anti-inflammatory agents in a rat model of antigen-induced arthritis

INTRODUCTION: Previously, secretory phospholipase A(2 )(sPLA(2)) inhibition has been used as an adjunct to conventional rheumatoid arthritis therapy in human clinical trials without significant improvement of arthritic pathology. In this study, we compared the efficacy of a potent and orally active...

Descripción completa

Detalles Bibliográficos
Autores principales:	Coulthard, Liam G, Costello, Jaclyn, Robinson, Brent, Shiels, Ian A, Taylor, Stephen M, Woodruff, Trent M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132024/ https://www.ncbi.nlm.nih.gov/pubmed/21401925 http://dx.doi.org/10.1186/ar3278

Ejemplares similares

Commentary: Beyond C4: Analysis of the complement gene pathway shows enrichment for IQ in patients with psychotic disorders and healthy controls
por: Coulthard, Liam G., et al.
Publicado: (2019)

Secretory Phospholipases A(2) in Plants
por: Mariani, María Elisa, et al.
Publicado: (2019)

Biology of Secretory Phospholipase A(2)
por: Boyanovsky, Boris B., et al.
Publicado: (2008)

Acidification in the epidermis and the role of secretory phospholipases
por: Chan, Aegean, et al.
Publicado: (2011)

A novel anti-inflammatory role for secretory phospholipase A(2) in immune complex-mediated arthritis
por: Boilard, Eric, et al.
Publicado: (2010)

Secretory Phospholipase A2s in Insulin Resistance and Metabolism
por: Kuefner, Michael S.
Publicado: (2021)

Role of secretory phospholipase A(2) in women with metabolic syndrome
por: Pop, D., et al.
Publicado: (2013)

Secretory phospholipase A2 in the pathogenesis of acute dengue infection
por: Jeewandara, Chandima, et al.
Publicado: (2016)

Secretory Phospholipase A(2) Enzymes in Acute Lung Injury
por: Letsiou, Eleftheria, et al.
Publicado: (2021)

Synergistic Effects of Secretory Phospholipase A(2) from the Venom of Agkistrodon piscivorus piscivorus with Cancer Chemotherapeutic Agents
por: Nelson, Jennifer, et al.
Publicado: (2013)

A secretory phospholipase A(2)-mediated neuroprotection and anti-apoptosis
por: Armugam, Arunmozhiarasi, et al.
Publicado: (2009)

Synergy between serum amyloid A and secretory phospholipase A(2)
por: Jayaraman, Shobini, et al.
Publicado: (2019)

Evaluation of Rhamnetin as an Inhibitor of the Pharmacological Effect of Secretory Phospholipase A2
por: Novo Belchor, Mariana, et al.
Publicado: (2017)

Secretory Phospholipase A(2)-IIA and Cardiovascular Disease: A Mendelian Randomization Study
por: Holmes, Michael V., et al.
Publicado: (2013)

Immunohistochemical study on the secretory host defense system with lysozyme and secretory phospholipase A2 throughout rat respiratory tract
por: MASUDA, Natsumi, et al.
Publicado: (2017)

A secretory phospholipase D hydrolyzes phosphatidylcholine to suppress rice heading time
por: Qu, Li, et al.
Publicado: (2021)

Inhibition of the activity of pro-inflammatory secretory phospholipase A(2) by acute phase proteins
por: Pruzanski, W., et al.
Publicado: (1996)

Lactadherin Inhibits Secretory Phospholipase A(2) Activity on Pre-Apoptotic Leukemia Cells
por: Nyegaard, Steffen, et al.
Publicado: (2013)

Secretory phospholipase A(2) modified HDL rapidly and potently suppresses platelet activation
por: Curcic, Sanja, et al.
Publicado: (2017)

Acid Sphingomyelinase, a Lysosomal and Secretory Phospholipase C, Is Key for Cellular Phospholipid Catabolism
por: Breiden, Bernadette, et al.
Publicado: (2021)

The Step Further to Understand the Role of Cytosolic Phospholipase A(2) Alpha and Group X Secretory Phospholipase A(2) in Allergic Inflammation: Pilot Study
por: Pniewska, Ewa, et al.
Publicado: (2014)

Clinical and biological role of secretory phospholipase A2 in acute respiratory distress syndrome infants
por: De Luca, Daniele, et al.
Publicado: (2013)

Ex Vivo Effect of Varespladib on Secretory Phospholipase A2 Alveolar Activity in Infants with ARDS
por: De Luca, Daniele, et al.
Publicado: (2012)

Group V Secretory Phospholipase A(2) Is Involved in Tubular Integrity and Sodium Handling in the Kidney
por: Silva-Filho, João Luiz, et al.
Publicado: (2016)

Suilyin Disrupts the Blood–Brain Barrier by Activating Group III Secretory Phospholipase A2
por: Sui, Yutong, et al.
Publicado: (2022)

Sinapicacid Inhibits Group IIA Secretory Phospholipase A(2) and Its Inflammatory Response in Mice
por: Giresha, Aladahalli S., et al.
Publicado: (2022)

Phospholipase D Stimulates Release of Nascent Secretory Vesicles from the trans-Golgi Network
por: Chen, Ye-Guang, et al.
Publicado: (1997)

Effect of polyunsaturated fatty acids on secretory phospholipase A2 type IIa in ectopic endometrial cells
por: Khanaki, Korosh, et al.
Publicado: (2012)

Modulation of the Pharmacological Activities of Secretory Phospholipase A2 from Crotalus durissus cascavella Induced by Naringin
por: Santos, Marcelo L., et al.
Publicado: (2011)

Differences between group X and group V secretory phospholipase A(2) in lipolytic modification of lipoproteins
por: Kamitani, Shigeki, et al.
Publicado: (2012)

Discrete Role for Cytosolic Phospholipase A(2)α in Platelets: Studies Using Single and Double Mutant Mice of Cytosolic and Group IIA Secretory Phospholipase A(2)
por: Wong, Dennis A., et al.
Publicado: (2002)

Effect of intensive insulin treatment on plasma levels of lipoprotein-associated phospholipase A(2) and secretory phospholipase A(2) in patients with newly diagnosed type 2 diabetes
por: Lin, Xiu-hong, et al.
Publicado: (2016)

Secretory phospholipase-A2 and fatty acid composition in oral reactive lesions: a cross-sectional study
por: Mesgarzadeh, Ali Hossein, et al.
Publicado: (2017)

Phospholipase D2 Modulates the Secretory Pathway in RBL-2H3 Mast Cells
por: Marchini-Alves, Claudia Maria Meirelles, et al.
Publicado: (2015)

Possible Involvement of Intracellular Calcium-Independent Phospholipase A(2) in the Release of Secretory Phospholipases from Mast Cells—Increased Expression in Ileal Mast Cells of Crohn’s Disease
por: Christerson, Ulrika, et al.
Publicado: (2019)

Tenidap sodium inhibits secretory non-pancreatic phospholipase A(2) synthesis by foetal rat calvarial osteoblasts
por: Pruzanski, W., et al.
Publicado: (1995)

Secretory phospholipase A2-IIa upregulates HER/HER2-elicited signaling in lung cancer cells
por: DONG, ZHONGYUN, et al.
Publicado: (2014)

Neutralization of Inflammation by Inhibiting In vitro and In vivo Secretory Phospholipase A(2) by Ethanol Extract of Boerhaavia diffusa L.
por: Giresha, Aladahalli S., et al.
Publicado: (2017)

Angiopoietins, Vascular Endothelial Growth Factors and Secretory Phospholipase A(2) in Ischemic and Non-Ischemic Heart Failure
por: Varricchi, Gilda, et al.
Publicado: (2020)

Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A(2)
por: Schevitz, R.W., et al.
Publicado: (1995)

Cannot write session to /tmp/vufind_sessions/sess_osquehapn1qnta3hs989q11f1o