A folate receptor beta-specific human monoclonal antibody recognizes activated macrophage of rheumatoid patients and mediates antibody-dependent cell-mediated cytotoxicity

INTRODUCTION: Folate receptor beta (FRβ) is only detectable in placenta and limited to some hematopoietic cells of myeloid lineage in healthy people. Studies have indicated that FRβ is over-expressed in activated macrophages in autoimmune diseases and some cancer cells. In this study we aimed to dev...

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Detalles Bibliográficos
Autores principales: Feng, Yang, Shen, Jiayin, Streaker, Emily D, Lockwood, Michael, Zhu, Zhongyu, Low, Philip S, Dimitrov, Dimiter S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132054/
https://www.ncbi.nlm.nih.gov/pubmed/21477314
http://dx.doi.org/10.1186/ar3312

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