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Endothelin Receptor A Antagonism Attenuates Renal Medullary Blood Flow Impairment in Endotoxemic Pigs

BACKGROUND: Endothelin-1 is a potent endogenous vasoconstrictor that contributes to renal microcirculatory impairment during endotoxemia and sepsis. Here we investigated if the renal circulatory and metabolic effects of endothelin during endotoxemia are mediated through activation of endothelin-A re...

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Detalles Bibliográficos
Autores principales:	Fenhammar, Johan, Andersson, Andreas, Forestier, Jakob, Weitzberg, Eddie, Sollevi, Alf, Hjelmqvist, Hans, Frithiof, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132177/ https://www.ncbi.nlm.nih.gov/pubmed/21760895 http://dx.doi.org/10.1371/journal.pone.0021534

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