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Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient

Infection is a leading cause of death in renal allograft recipients. Apart from the immunosuppressive drugs, immunomodulatory viral infections also predispose the recipient to many opportunistic infections. Kala-azar in renal allograft recipients is infrequently reported even in endemic areas. In ma...

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Autores principales: Prasad, N., Gupta, A., Sharma, R. K., Gopalakrishnan, S., Agrawal, V., Jain, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132335/
https://www.ncbi.nlm.nih.gov/pubmed/21769179
http://dx.doi.org/10.4103/0971-4065.78064
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author Prasad, N.
Gupta, A.
Sharma, R. K.
Gopalakrishnan, S.
Agrawal, V.
Jain, M.
author_facet Prasad, N.
Gupta, A.
Sharma, R. K.
Gopalakrishnan, S.
Agrawal, V.
Jain, M.
author_sort Prasad, N.
collection PubMed
description Infection is a leading cause of death in renal allograft recipients. Apart from the immunosuppressive drugs, immunomodulatory viral infections also predispose the recipient to many opportunistic infections. Kala-azar in renal allograft recipients is infrequently reported even in endemic areas. In majority of cases, there was delay in diagnosis and treatment. We report a case of renal allograft recipient, where we faced a diagnostic dilemma because of coinfection of cytomegalovirus and visceral leishmaniasis (kala-azar). Kala-azar was successfully treated with amphotericin B. Kala-azar should always be kept as differential diagnosis in patients with pyrexia and cytopenia, even in the absence of splenomegaly in patients residing in an endemic zone.
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spelling pubmed-31323352011-07-18 Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient Prasad, N. Gupta, A. Sharma, R. K. Gopalakrishnan, S. Agrawal, V. Jain, M. Indian J Nephrol Case Report Infection is a leading cause of death in renal allograft recipients. Apart from the immunosuppressive drugs, immunomodulatory viral infections also predispose the recipient to many opportunistic infections. Kala-azar in renal allograft recipients is infrequently reported even in endemic areas. In majority of cases, there was delay in diagnosis and treatment. We report a case of renal allograft recipient, where we faced a diagnostic dilemma because of coinfection of cytomegalovirus and visceral leishmaniasis (kala-azar). Kala-azar was successfully treated with amphotericin B. Kala-azar should always be kept as differential diagnosis in patients with pyrexia and cytopenia, even in the absence of splenomegaly in patients residing in an endemic zone. Medknow Publications 2011 /pmc/articles/PMC3132335/ /pubmed/21769179 http://dx.doi.org/10.4103/0971-4065.78064 Text en Copyright: © Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Prasad, N.
Gupta, A.
Sharma, R. K.
Gopalakrishnan, S.
Agrawal, V.
Jain, M.
Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient
title Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient
title_full Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient
title_fullStr Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient
title_full_unstemmed Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient
title_short Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient
title_sort cytomegalovirus and leishmania donovani coinfection in a renal allograft recipient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132335/
https://www.ncbi.nlm.nih.gov/pubmed/21769179
http://dx.doi.org/10.4103/0971-4065.78064
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