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Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient
Infection is a leading cause of death in renal allograft recipients. Apart from the immunosuppressive drugs, immunomodulatory viral infections also predispose the recipient to many opportunistic infections. Kala-azar in renal allograft recipients is infrequently reported even in endemic areas. In ma...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132335/ https://www.ncbi.nlm.nih.gov/pubmed/21769179 http://dx.doi.org/10.4103/0971-4065.78064 |
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author | Prasad, N. Gupta, A. Sharma, R. K. Gopalakrishnan, S. Agrawal, V. Jain, M. |
author_facet | Prasad, N. Gupta, A. Sharma, R. K. Gopalakrishnan, S. Agrawal, V. Jain, M. |
author_sort | Prasad, N. |
collection | PubMed |
description | Infection is a leading cause of death in renal allograft recipients. Apart from the immunosuppressive drugs, immunomodulatory viral infections also predispose the recipient to many opportunistic infections. Kala-azar in renal allograft recipients is infrequently reported even in endemic areas. In majority of cases, there was delay in diagnosis and treatment. We report a case of renal allograft recipient, where we faced a diagnostic dilemma because of coinfection of cytomegalovirus and visceral leishmaniasis (kala-azar). Kala-azar was successfully treated with amphotericin B. Kala-azar should always be kept as differential diagnosis in patients with pyrexia and cytopenia, even in the absence of splenomegaly in patients residing in an endemic zone. |
format | Online Article Text |
id | pubmed-3132335 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Medknow Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-31323352011-07-18 Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient Prasad, N. Gupta, A. Sharma, R. K. Gopalakrishnan, S. Agrawal, V. Jain, M. Indian J Nephrol Case Report Infection is a leading cause of death in renal allograft recipients. Apart from the immunosuppressive drugs, immunomodulatory viral infections also predispose the recipient to many opportunistic infections. Kala-azar in renal allograft recipients is infrequently reported even in endemic areas. In majority of cases, there was delay in diagnosis and treatment. We report a case of renal allograft recipient, where we faced a diagnostic dilemma because of coinfection of cytomegalovirus and visceral leishmaniasis (kala-azar). Kala-azar was successfully treated with amphotericin B. Kala-azar should always be kept as differential diagnosis in patients with pyrexia and cytopenia, even in the absence of splenomegaly in patients residing in an endemic zone. Medknow Publications 2011 /pmc/articles/PMC3132335/ /pubmed/21769179 http://dx.doi.org/10.4103/0971-4065.78064 Text en Copyright: © Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Prasad, N. Gupta, A. Sharma, R. K. Gopalakrishnan, S. Agrawal, V. Jain, M. Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient |
title | Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient |
title_full | Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient |
title_fullStr | Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient |
title_full_unstemmed | Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient |
title_short | Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient |
title_sort | cytomegalovirus and leishmania donovani coinfection in a renal allograft recipient |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132335/ https://www.ncbi.nlm.nih.gov/pubmed/21769179 http://dx.doi.org/10.4103/0971-4065.78064 |
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