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H5N1 Influenza Vaccine Formulated with AS03(A) Induces Strong Cross-Reactive and Polyfunctional CD4 T-Cell Responses

OBJECTIVE: Adjuvantation of an H5N1 split-virion influenza vaccine with AS03(A) substantially reduces the antigen dose required to produce a putatively protective humoral response and promotes cross-clade neutralizing responses. We determined the effect of adjuvantation on antibody persistence and B...

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Detalles Bibliográficos
Autores principales:	Moris, Philippe, van der Most, Robbert, Leroux-Roels, Isabel, Clement, Frédéric, Dramé, Mamadou, Hanon, Emmanuel, Leroux-Roels, Geert G., Van Mechelen, Marcelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132412/ https://www.ncbi.nlm.nih.gov/pubmed/21174144 http://dx.doi.org/10.1007/s10875-010-9490-6

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